货号：AB1537

品牌：Merck Millipore

规格：1EA

目录价：￥4986.69

市场价格：￥4238.69

会员价格：￥3989.35

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Dopamine β Hydroxylase Antibody, C-terminus | AB1537 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Dopamine Beta Hydroxylase (DbetaH) C-terminal. By immunoblot the antibody specifically reacts with a single (or double) band(s) of M.W. »70-75,000 in samples of SDS-solubilized, DTT-reduced human adrenal medulla subjected to SDS-PAGE. View All» Epitope: C-terminus View All» Immunogen: Synthetic peptide, CPTSQGRSPAGPTVVSI-amide, from C-terminal region of human (DbetaH). View All» Species Reactivity:

• Human

• Monkey
  View All» Application Notes: Immunoblotting: 1:250-1:1,000 on human, monkey and bovine adrenal medulla. Immunohistochemistry: 1:250-1:1,000, staining was evaluated in the locus coeruleus of formaldehyde-fixed, cryopreserved human and monkey brain. Showed strong staining on both human and monkey. Optimal working dilutions must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. View All» Storage Conditions: Maintain at -20 to -70°C in undiluted aliquots for up to six months. Avoid repeated freeze-thaw cycles. View All» UniProt Number: P09172 View All» Entrez Gene Number: NM_000787.3 View All» Gene Symbol:
  • DBH

  • DBM

  • EC 1.14.17.1 [Contains: Soluble dopamine beta-hydroxylase].
    View All» Alternate Names: DBH View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Entrez Gene Summary: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. View All» UniProt Summary: FUNCTION: SwissProt: P09172 # Conversion of dopamine to noradrenaline.COFACTOR: Binds 1 PQQ per subunit. & Binds 2 copper ions per subunit.SIZE: 617 amino acids; 69065 Da SUBUNIT: Homotetramer composed of two non-covalently bound disulfide-linked dimers.SUBCELLULAR LOCATION: Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. & Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single- pass type II membrane protein (Potential).DISEASE: SwissProt: P09172 # Defects in DBH are the cause of DBH deficiency [MIM:223360]; also called norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.SIMILARITY: SwissProt: P09172 ## Belongs to the copper type II ascorbate-dependent monooxygenase family. & Contains 1 DOMON domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Dopamine β Hydroxylase Antibody, C-terminus | AB1537 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Cytoplasmic View All» Format: Affinity Purified View All» Host: Sheep View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-152175.htm
      © Merck Millipore代理AB1537 Anti-Dopamine beta Hydroxylase Antibody, CT，产品报价联系微信jinshanbio