货号：AB15408

品牌：Merck Millipore

规格：50UL

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-APG10 Antibody | AB15408 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: APG10 [Autophagy-related protein 10, APG10-like, ATG10]. View All» Immunogen: Synthetic peptide corresponding to a region within the C-terminus of human APG10 protein. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The APG10 protein plays a role in the conjugation of APG5 to APG12 and this conjugate is required for elongation of the isolation membrane to form a complete spherical autophagosome. The APG10 is able to interact with MAP1LC3A and with APG5 and APG7. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:200-1:1,000 Immunocytochemistry: 1:200-1:1,000 Immunohistochemistry: 1:200-1:1,000 Optimal working dilutions must be determined by end user. View All» Purification Method: Serum View All» Presentation: Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: Q9H0Y0 View All» Entrez Gene Number: NM_031482.3 View All» Gene Symbol:

• ATG10

• APG10

• DKFZP586I0418

• APG10L

• APG10-like

• ORFNames=PP12616

• FLJ13954

• pp12616
  View All» Alternate Names: Autophagy-related protein 10, APG10-like, ATG10 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» Entrez Gene Summary: Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q9H0Y0 # Plays a role in autophagy (By similarity). ATG12- conjugating enzyme (E2-like enzyme), likely serves as an ATG5- recognition molecule.SIZE: 220 amino acids; 25279 Da SUBUNIT: Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7 (By similarity).SUBCELLULAR LOCATION: Cytoplasm (Probable).SIMILARITY: SwissProt: Q9H0Y0 ## Belongs to the ATG10 family. View All» Brand Family: Chemicon View All» Product Name: Anti-APG10 Antibody | AB15408 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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