货号：AB15410

品牌：Merck Millipore

规格：

目录价：￥5054.00

市场价格：￥4295.90

会员价格：￥4043.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-APG12 Antibody | AB15410 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: APG12 [Autophagy-related protein 12, APG12-like, ATG12]. View All» Immunogen: Synthetic peptide corresponding to a region within the N-terminus of human APG12 protein. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The APG12 system is one of the ubiquitin-like protein conjugation systems conserved in eukaryotes. APG12 conjugation of APG5 is required for elongation of the isolation membrane to form a complete spherical autophagosome. Discovery of the APG12 system has facilitated our understanding of the molecular mechanism of autophagosome formation. View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western blot: 1:200-1:1,000 Immunocytochemistry: 1:200-1:1,000 Immunohistochemistry: 1:200-1:1,000 Optimal working dilutions must be determined by end user. View All» Purification Method: Serum View All» Presentation: Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: O94817 View All» Entrez Gene Number: NM_004707.2 View All» Gene Symbol:
  • ATG12

  • APG12L

  • APG12-like

  • HAPG12

  • APG12
    View All» Alternate Names: Autophagy-related protein 12, APG12-like, ATG12 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry

    • Immunohistochemistry
      View All» Entrez Gene Summary: Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: O94817 # Required for autophagy.SIZE: 140 amino acids; 15113 Da SUBUNIT: Conjugated to ATG5.SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Ubiquitous.SIMILARITY: SwissProt: O94817 ## Belongs to the ATG12 family. View All» Brand Family: Chemicon View All» Product Name: Anti-APG12 Antibody | AB15410 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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