货号：AB15414

品牌：Merck Millipore

规格：50UL

目录价：￥5820.00

市场价格：￥4947.00

会员价格：￥4656.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP1LC3 C Antibody | AB15414 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: MAP1LC3 C [Microtubule-associated proteins 1A/1B light chain 3C, MAP1A/1B LC3 C, MAP1 LC3, LC3 C]. View All» Immunogen: Synthetic peptide corresponding to a region within the N-terminus of human MAP1LC3 C protein. View All» Background Information: Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The human MAP1LC3 protein is homologous with the rat Map1LC3 and with yeast APG8. These proteins are likely to be involved in the formation of autophagosomal vacuoles (autophagosomes). View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western blot: 1:100-1:1,000 Immunocytochemistry: 1:100-1:1,000 Immunohistochemistry: 1:100-1:1,000 Optimal working dilutions must be determined by end user. View All» Purification Method: Serum View All» Presentation: Lyophilized. Reconstitute with 50 uL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. View All» Storage Conditions: Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. View All» UniProt Number: Q9BXW4 View All» Entrez Gene Number: NM_001004343.1 View All» Gene Symbol: MAP1LC3C View All» Alternate Names: Microtubule-associated proteins 1A/1B light chain 3C, MAP1A/1B LC3 C, MAP1 LC3, LC3 C View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» UniProt Summary: FUNCTION: SwissProt: Q9BXW4 # Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity).SIZE: 147 amino acids; 16852 Da SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity).SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid- anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes.TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary.PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.SIMILARITY: SwissProt: Q9BXW4 ## Belongs to the MAP1 LC3 family. View All» Brand Family: Chemicon View All» Product Name: Anti-MAP1LC3 C Antibody | AB15414 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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