货号：AB1549

品牌：Merck Millipore

规格：

目录价：￥3732.00

市场价格：￥3172.20

会员价格：￥2985.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Brain Natriuretic Peptide Antibody | AB1549 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Brain Natriuretic Peptide View All» Molecular Weight: 13.6 kDa View All» Epitope: C-Terminus View All» Immunogen: Synthetic Peptide View All» Background Information: Brain natriuretic peptide is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes in the ventricles. At the time of release, a co-secreted 76 amino acid N-terminal fragment (NT-proBNP) is also released with BNP. BNP binds to and activates NPRA in a similar fashion to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. View All» Species Reactivity: Rat View All» Application Notes: Western blot Analysis: 0.5 µg/mL detected BNP in 10 µg of Rat Spleen LysateOptimal working dilutions must be determined by the end user. View All» Control: Tested on Rat Spleen Lysate View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified Antibody in PBS with 0.1% NaN3 View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: P16860 View All» Entrez Gene Number: NM_002521.2 View All» Gene Symbol:

• NPPB

• BNP

• OTTHUMP00000044486
  View All» Alternate Names: BNP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Western Blotting
    View All» Entrez Gene Summary: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. View All» UniProt Summary: FUNCTION: SwissProt: P16860 # Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body's salt and water balance. Improves heart function.SIZE: 134 amino acids; 14726 Da SUBUNIT: Interacts with NPR3.SUBCELLULAR LOCATION: Secreted.TISSUE SPECIFICITY: Brain and also in atria, but at much lower levels than ANP.SIMILARITY: SwissProt: P16860 ## Belongs to the natriuretic peptide family. View All» Brand Family: Chemicon View All» Product Name: Anti-Brain Natriuretic Peptide Antibody | AB1549 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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