货号：AB15510

品牌：Merck Millipore

规格：50Ug

目录价：￥6281.00

市场价格：￥5338.85

会员价格：￥5024.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuroligin 2 Antibody | AB15510 View All» Promotional Text: Special Offer on Antibodies! Click Here! View All» Trade Name: Chemicon (Millipore) View All» Specificity: Neuroligin 2 (NLGN2). View All» Immunogen: Synthetic peptide near the C-terminus of human Neuroligin 2 View All» Background Information: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1-10 μg/mL using ECL. Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 μg/mLELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well.Optimal working dilutions must be determined by end user. View All» Presentation: Liquid in PBS with 0.1% BSA. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q8NFZ4 View All» Entrez Gene Number: NM_020795.2 View All» Gene Symbol:

• NLGN2

• KIAA1366
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • ELISA
    View All» Entrez Gene Summary: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. View All» UniProt Summary: FUNCTION: SwissProt: Q8NFZ4 # Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures.SIZE: 835 amino acids; 90820 Da SUBUNIT: Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts with INADL (By similarity). Probably interacts through its C-terminus with DLG4 third PDZ domain.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).SIMILARITY: SwissProt: Q8NFZ4 ## Belongs to the type-B carboxylesterase/lipase family. View All» Brand Family: Chemicon View All» Product Name: Anti-Neuroligin 2 Antibody | AB15510 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Host: Rabbit View All»
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