货号：AB15522

品牌：Merck Millipore

规格：

目录价：￥5054.00

市场价格：￥4295.90

会员价格：￥4043.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuronal pentraxin 1 Receptor Antibody | AB15522 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Neuronal pentraxin 1 Receptor (NPXR1). View All» Immunogen: Synthetic peptide near the C-terminus of mouse NPXR1 View All» Background Information: Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPXR1 (Neuronal Pentraxin Receptor 1) a 493aa protein in mouse, 494 in rat, and 499aa in human. The predominant form of NPXR contains a putative NH2 terminal transmembrane and all forms are glycosylated. It shows 49 and 48% homology with NPX1 and NPX2 respectively. NPXR message is expressed in neuronal regions that express NPX1 and NPX2. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Other species have not yet been tested. The immunogen sequence is 100% conserved in rat, and human NPXR1. View All» Application Notes: Western blot: 1-10 µg/mL using ECL. Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL ELISA: 0.5-1 µg/mL using control peptide. Optimal working dilutions must be determined by end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in PBS with 0.1% BSA. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: O95502 View All» Entrez Gene Number: NM_014293.2 View All» Gene Symbol:

• NPTXR

• NPR
  View All» Alternate Names: NPXR1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. View All» UniProt Summary: COFACTOR: Binds 2 calcium ions per subunit (By similarity).SIZE: 499 amino acids; 52718 Da SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential).SIMILARITY: SwissProt: O95502 ## Contains 1 pentaxin domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Neuronal pentraxin 1 Receptor Antibody | AB15522 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Purified View All» Host: Rabbit View All»
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