货号：AB15554-50UL

品牌：Merck Millipore

规格：1EA

目录价：￥5125.68

市场价格：￥4356.83

会员价格：￥4100.54

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-AT2 Receptor Antibody | AB15554-50UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes AT2 Receptor (Angiotensin II receptory type 2, AGTR2). View All» Immunogen: Purified peptide from the N-terminus of rat AT2 Receptor (Accession number P35351). View All» Species Reactivity:

• Mouse

• Rat
  View All» Non-Reactive Species: Human View All» Application Notes: Western blot: 1:200-1:500 using ECL on rat brain and mouse MS1 cell lysate. Dilutions should be made using a carrier protein such as BSA (1-3%). Optimal working dilutions must be determined by the end user. View All» Control: Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P50052 View All» Entrez Gene Number: NM_000686.4 View All» Gene Symbol:
  • AGTR2

  • MRX88

  • AT2

  • ATGR2
    View All» Alternate Names: Angiotensin II receptory type 2, AGTR2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame. View All» UniProt Summary: FUNCTION: SwissProt: P50052 # Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.SIZE: 363 amino acids; 41184 Da SUBUNIT: Interacts with MTUS1.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.SIMILARITY: SwissProt: P50052 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-AT2 Receptor Antibody | AB15554-50UL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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