货号：AB15582

品牌：Merck Millipore

规格：

目录价：￥4774.00

市场价格：￥4057.90

会员价格：￥3819.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ASH1 Antibody | AB15582 View All» Replaces: AB5696 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: ASH1 (MASH1, mammalian achaete-scute homolog 1). By Western blot the antibody recognizes a band at ~30 kDa on mouse hippocampus lysate. View All» Immunogen: Synthetic peptide. View All» Species Reactivity: Mouse View All» Application Notes: Western blot: 0.5-1.0 μg/mL on mouse hippocampus lysate. Optimal working dilutions must be determined by end user. View All» Purification Method: Immunoaffinity purified View All» Presentation: Liquid in PBS with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P50553 View All» Entrez Gene Number: NP_004307 View All» Gene Symbol:

• ASCL1

• HASH1

• MASH1

• ASH1
  View All» Alternate Names:
  • MASH1

  • KMT2H

  • Mammalian Achaete-scute homolog 1

  • Class A basic helix-loop-helix protein 46

  • ASH-1
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests that it may also play a role in tumor formation. View All» UniProt Summary: FUNCTION: SwissProt: P50553 # May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Activates transcription by binding to the E box (5'-CANNTG-3').SIZE: 236 amino acids; 25454 Da SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3.SUBCELLULAR LOCATION: Nucleus (Probable).SIMILARITY: SwissProt: P50553 ## Contains 1 basic helix-loop-helix (bHLH) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-ASH1 Antibody | AB15582 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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