货号：AB15708B

品牌：Merck Millipore

规格：

目录价：￥4891.00

市场价格：￥4157.35

会员价格：￥3912.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Beta III Tubulin, Biotin conjugate Antibody | AB15708B View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: 50 kDa calculated View All» Immunogen: Synthetic peptide from human Beta III Tubulin View All» Background Information: Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions. View All» Species Reactivity:

• Rat

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology. View All» Control: Rat E18 cortex cells View All» Quality Assurance: Evaluated by Immunocytochemistry in rat E18 cortex cells.Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q13509 View All» Entrez Gene Number: NP_006077 View All» Gene Symbol:
  • TUBB3

  • TUBB4

  • MC1R

  • beta-4
    View All» Alternate Names:
    • Tubulin beta-4

    • Tubulin beta-III

    • tubulin, beta 3

    • tubulin, beta, 4

    • Beta III Tubulin
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunocytochemistry View All» Entrez Gene Summary: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. View All» UniProt Summary: FUNCTION: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.SIZE: 450 amino acids; 50433 Da SUBUNIT: Dimer of alpha and beta chains.DOMAIN: The highly acidic C-terminal region may bind cations such as calcium.SIMILARITY: Belongs to the tubulin family. View All» Product Name: Anti-Beta III Tubulin, Biotin conjugate View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Biotin View All» Host: Rabbit View All»
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