货号：AB1585

品牌：Merck Millipore

规格：50UL

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Dopamine β Hydroxylase Antibody | AB1585 View All» Replaces: AB145 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Dopamine beta hydroxylase. AB1585 reacts with a single band on Western blots of bovine adrenal homogenates and stains only cells known to contain DBH, such as sympathetic neurons, adrenal medullary cells and central adrenergic neurons. Staining is abolished by preincubation with enzyme. View All» Molecular Weight: 69 kDa View All» Immunogen: Native enzyme from bovine adrenal glands. View All» Species Reactivity:

• Bovine

• Guinea Pig

• Human

• Rat

• Rabbit

• Feline
  View All» Application Notes: Immunohistochemistry: 1:2,000 on rabbit and guinea pig using an ABC detection method. Western blot RIA Inhibitory studies in vivo and in vitro. Optimal working dilutions must be determined by the end user. View All» Control: Brain (Striatum/Substantia Nigra) View All» Purification Method: Unpurified View All» Presentation: Rabbit Serum. Lyophilized, no preservatives. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. View All» Storage Conditions: Maintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. Glycerol can be added 1:1 for additional stability. View All» UniProt Number: P09172 View All» Entrez Gene Number: NM_000787.3 View All» Gene Symbol:
  • DBH

  • DBM

  • EC 1.14.17.1 [Contains: Soluble dopamine beta-hydroxylase].
    View All» Alternate Names: DBH; Dopamine beta-monooxygenase View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Affects Function

    • Radioimmunoassay

    • Western Blotting
      View All» Entrez Gene Summary: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. View All» UniProt Summary: FUNCTION: SwissProt: P09172 # Conversion of dopamine to noradrenaline.COFACTOR: Binds 1 PQQ per subunit. & Binds 2 copper ions per subunit.SIZE: 617 amino acids; 69065 Da SUBUNIT: Homotetramer composed of two non-covalently bound disulfide-linked dimers.SUBCELLULAR LOCATION: Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. & Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single- pass type II membrane protein (Potential).DISEASE: SwissProt: P09172 # Defects in DBH are the cause of DBH deficiency [MIM:223360]; also called norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.SIMILARITY: SwissProt: P09172 ## Belongs to the copper type II ascorbate-dependent monooxygenase family. & Contains 1 DOMON domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Dopamine β Hydroxylase Antibody | AB1585 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μL View All» Target / Localization: Cytoplasmic View All» Format: Serum View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-152482.htm
      © Merck Millipore代理AB1585 Anti-Dopamine β Hydroxylase Antibody;抗多巴胺β羟化酶抗体store at -20℃，产品报价联系微信jinshanbio