货号：AB15850

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody | AB15850 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: RabGDI alpha (Rab GDP dissociation inhibitor alpha). By Western blot the antibody reacts with a band at ~ 51-55 kDa on rat brain lysate. View All» Immunogen: Synthetic peptide from the C-terminus of rat RabGDI alpha. View All» Species Reactivity: Rat View All» Presentation: Liquid in PBS with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: P31150 View All» Entrez Gene Number: NM_001493.1 View All» Gene Symbol:

• GDI1

• OPHN2

• MRX48

• XAP4

• RABGD1A

• Oligophrenin-2

• GDIL

• RABGDIA

• XAP-4

• MRX41

• GDI-1

• FLJ41411
  View All» Key Applications: Western Blotting View All» Entrez Gene Summary: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. View All» UniProt Summary: FUNCTION: SwissProt: P31150 # Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.SIZE: 447 amino acids; 50583 Da SUBCELLULAR LOCATION: Cytoplasm (By similarity).TISSUE SPECIFICITY: Brain; predominant in neural and sensory tissues.DISEASE: SwissProt: P31150 # Defects in GDI1 are the cause of non-syndromic mental retardation X-linked type 41 (MRX41) [MIM:309541]; also known as MRX3. Mental retardation is characterized by significantly sub- average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. & Defects in GDI1 are the cause of non-syndromic mental retardation X-linked type 48 (MRX48) [MIM:309541]; also known as MRX3.SIMILARITY: SwissProt: P31150 ## Belongs to the Rab GDI family. View All» Brand Family: Chemicon View All» Product Name: Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody | AB15850 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 1 View All» Format: Affinity Purified View All» Host: Rabbit View All»
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