货号：AB15882

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-HuC Antibody | AB15882 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: HuC. By Western blot the antibody reacts with a band at ~ 39 kDa on adult rat brain lysate and rat spinal cord lysate. An additional band at ~ 25 kDa may be seen depending on sample and antibody concentration used. View All» Molecular Weight: 39.5 kDa View All» Epitope: N-Terminus View All» Immunogen: Synthetic peptide near the N-terminus human/rat/mouse HuC. View All» Background Information: Hu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. RNA binding protein HuC promotes neuronal development in both the central and the peripheral nervous systems. HuC antibodies are are also used as markers for developing neurons. View All» Species Reactivity:

• Rat

• Human
  View All» Control: Tested on adult rat brain lysate View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified Antibody in PBS with 0.1% NaN3 View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. View All» UniProt Number: Q14576 View All» Entrez Gene Number:
  • NM_001420.3

  • NM_032281.2
    View All» Gene Symbol:
    • ELAVL3

    • PLE21

    • HUCL

    • MGC20653

    • HUC

    • HuC

    • DKFZp547J036
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: Q14576 # May be involved in neuronal differentiation and maintenance.SIZE: 367 amino acids; 39547 Da TISSUE SPECIFICITY: Brain specific.SIMILARITY: SwissProt: Q14576 ## Belongs to the RRM elav family. & Contains 3 RRM (RNA recognition motif) domains. View All» Brand Family: Chemicon View All» Product Name: Anti-HuC Antibody | AB15882 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Very early marker, Nuclear View All» Format: Affinity Purified View All» Host: Rabbit View All»
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