货号：AB1590P

品牌：Merck Millipore

规格：50Ug

目录价：￥6434.00

市场价格：￥5468.90

会员价格：￥5147.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168) | AB1590P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Specific for Adenosine A3 receptor. Based on mRNA studies, the A3R has been found in rat testis and lung, kidneys, heart and brain. Other studies have found the mRNA to be highest in lung, spleen and pineal glands and moderate levels in brain kidney and testis. View All» Epitope: extracellular (a.a. 154-168) View All» Immunogen: Amino acid sequence corresponding to the 3rd extracellular domain (15 amino acids) of the rat A3R gene. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1-10 micrograms per mL: A3 receptors are different sizes in different species & tissues; A3R from rat brain membranes runs as a 40kDa band, 52kDa in rabbit uroepithelium membranes (Yu, W et al. Am J. Physiol Cell Physiol 2006 in press); use proteinase inhibitors and membrane preparations for best signals. ELISA: 1:10,000-1:50,000 (50-100 ng A3R peptide (Catalog Number AG294)/well) Immunocytochemistry: Caufield, 2003. Light 2% PFA fixation 5-10 minutes --long fixations lower staining intensity. Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P33765 View All» Entrez Gene Number:

• NM_000677.3

• NM_001081976.1

• NM_020683.6
  View All» Gene Symbol:
  • ADORA3

  • AD026

  • RP11-552M11.7

  • A3AR

  • bA552M11.5

  • ORFNames=UNQ1931/PRO4406
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunocytochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P33765 # Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.SIZE: 318 amino acids; 36185 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.PTM: Phosphorylation on Ser-317 may be crucial for rapid desensitization (By similarity).SIMILARITY: SwissProt: P33765 ## Belongs to the G-protein coupled receptor 1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168) | AB1590P View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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