Merck Millipore代理AB1592P Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B;store at -20℃

2025-06-27

货号:AB1592P

品牌:Merck Millipore

规格:10Ug

目录价:¥6127.00

市场价格:¥5207.95

会员价格:¥4901.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B | AB1592P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: NMDAR2C. Immunolabels the 140 kD NMDAR2C subunit of the NMDA receptor. Also reacts with NMDAR2A and NMDAR2B by Western blot (180 kD). View All» Epitope: N-terminus View All» Immunogen: N-Terminal Fusion Protein of the NMDAR2C View All» Species Reactivity: Rat View All» Application Notes: Western blotting 1:100-1:200 Immunoprecipitation: 3 μL will (under the appropriate conditions) quantitatively immunoprecipitate all NMDAR2C in 200 μg of rat cerebellum. Not recommended for use in immunohistochemistry since the antibody also reacts with NMDAR2A and NMDAR2B. Optimal working dilutions must be determined by the end user. View All» Applications Not Recommended: Immunohistochemistry View All» Presentation: Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM), some residual salt may be present. Reconstitute with 50 μL of PBS. View All» Storage Conditions: Maintain lyophilized antibody at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q14957 View All» Entrez Gene Number: NM_000835.3 View All» Gene Symbol:

  • GRIN2C

  • Glutamate

  • NR2C

  • NMDAR2C

    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

      View All» Entrez Gene Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). View All» UniProt Summary: FUNCTION: SwissProt: Q14957 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.SIZE: 1233 amino acids; 134240 Da SUBUNIT: Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Mainly in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.SIMILARITY: SwissProt: Q14957 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family. View All» Brand Family: Chemicon View All» Product Name: Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B | AB1592P View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 10 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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