货号：AB1629

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Hexokinase Type II Antibody | AB1629 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts on immunoblot with rat Hexokinase Type II isozyme (102 kDa). No reactivity with rat Hexokinase Type I or III isozymes. View All» Immunogen: C-Terminal sequence of rat Hexokinase Type II (IREAGQR). View All» Species Reactivity: Rat View All» Application Notes: Immunoblot: 1:1,000 - 1:2,000* *Antibody may be used at a higher dilution with lower background if ECL (enhanced chemiluminescence) is used to develop the blot. Optimal working dilutions must be determined by the end user. View All» Presentation: Rabbit antiserum. Liquid. Contains no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P52789 View All» Entrez Gene Number: NM_000189.4 View All» Gene Symbol:

• HK2

• HKII

• Hexokinase-2

• HXK2

• DKFZp686M1669

• EC 2.7.1.1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. View All» UniProt Summary: SIZE: 917 amino acids; 102380 Da SUBUNIT: Monomer (By similarity).SUBCELLULAR LOCATION: Mitochondrion outer membrane (By similarity). Note=Its hydrophobic N-terminal sequence may be involved in membrane binding (By similarity).TISSUE SPECIFICITY: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.DOMAIN: SwissProt: P52789 The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.SIMILARITY: Belongs to the hexokinase family.MISCELLANEOUS: In vertebrates there are four major glucose- phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). View All» Brand Family: Chemicon View All» Product Name: Anti-Hexokinase Type II Antibody | AB1629 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 500 µL View All» Format: Serum View All» Host: Rabbit View All»
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