Merck Millipore代理AB1726 Anti-Connexin 40 Antibody;抗连接蛋白40抗体store at +2℃ to +8℃

2025-06-27

货号:AB1726

品牌:Merck Millipore

规格:50Ug

目录价:¥5513.00

市场价格:¥4686.05

会员价格:¥4410.40

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Connexin 40 Antibody | AB1726 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with mouse connexin 40. View All» Molecular Weight: 40 kDa View All» Immunogen: Anti-Connexin 40 is made against a 19 amino acid peptide sequence within the C-terminal cytoplasmic domain of mouse C×40 (2). Peptide sequence is conserved in human and rat Cx40 (100%), chicken Cx42 (77%), human Cx50 (87%), rat Cx50 (81%) and sheep Cx49 (87%). View All» Background Information: Mouse Connexin 40 is a 358 amino acid gap junction protein with a predicted M.W. of ~40 kDa. It is prominently expressed in lung, heart and skin (see reviews: Kumar & Giula 1996; White, 1995; Evans, 1994; Beyer , 1990; Henneman, 1992; Traub, 1994; Goliger & Paul 1994). One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. View All» Species Reactivity:

  • Human

  • Mouse

  • Rat

    View All» Species Reactivity Note: Human, mouse, and rat. Reactivity with other species has not been determined. View All» Application Notes: ELISA: A previous lot of this antibody was used at 1:100,000 using 50-100 ng C×40 control peptide per well.Western Blot Analysis:A previous lot of this antibody was used at 1:1000 dilutionOptimal working dilutions must be determined by end user. View All» Control: Placenta lysate. View All» Quality Assurance: Evaluated by Western Blot on Jurkat lysates.Western Blot Analysis: A 1:1000 dilution of this lot detected Connexin 40 in 10 μg of Jurkat lysates. View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 15 mM NaCl containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P36382 View All» Entrez Gene Number: NP_005257 View All» Gene Symbol:
    • GJA5

    • CX40

    • Connexin-40

    • MGC11185

    • Cx40

      View All» Alternate Names:
      • Cx40

      • Gap Junction alpha-5 Protein

      • CxA-5

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • ELISA

        • Immunoprecipitation

        • Western Blotting

          View All» Entrez Gene Summary: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq] View All» UniProt Summary: FUNCTION: SwissProt: P36382 # One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.SIZE: 358 amino acids; 40380 Da SUBUNIT: A connexon is composed of a hexamer of connexins.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.DISEASE: SwissProt: P36382 # Defects in GJA5 are the cause of atrial fibrillation type 4 (ATFB4) [MIM:108770]; also known as atrial standstill. ATFB is characterized by rapid and irregular activation of the atrium.SIMILARITY: SwissProt: P36382 ## Belongs to the connexin family. Alpha-type (group II) subfamily View All» Brand Family: Chemicon View All» Product Name: Anti-Connexin 40 Antibody | AB1726 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»

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