货号：AB18000

品牌：Merck Millipore

规格：EA

目录价：￥3708.00

市场价格：￥3151.80

会员价格：￥2966.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Zebrafish Integrin beta3 Antibody | AB18000 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: The antibody recognizes zebrafish Integrin beta3. View All» Molecular Weight: ~ 100 kDa is observed; the calculated MW of 88 kDa. View All» Epitope: 0 View All» Immunogen: Recombinant protein corresponding to zebrafish Integrin beta3. View All» Background Information: Integrin beta3 is a transmembrane glycoprotein that forms noncovalent complexes with various alpha integrin subunits to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. Heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins in extracellular matrix and/or adjacent cells. Interactions between integrins and extracellular matrix lead to activation of signal transduction pathways. Phosphorylation of tyrosine 773 on integrin beta3 activates the receptor and promotes cell adhesion.Tyr773 is commonly referred to as Tyr747, the corresponding site in the chicken integrin beta3 protein. View All» Species Reactivity: Zebrafish View All» Control: Zebrafish Integrin beta3 transfected and nontransfected CHO cell lysates. View All» Quality Assurance: Evaluated by Western blot in zebrafish Integrin beta3 transfected and nontransfected CHO cell lysates.Western blot Analysis: 0.1 µg/mL of this antibody detected Integrin beta3 in transfected and nontransfected CHO cell lysates. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q3LTM5 View All» Entrez Gene Number: NP_001076417 View All» Gene Symbol:

• ITGB3

• CD61

• GP3A

• GPIIIa
  View All» Alternate Names:
  • CD61 antigen

  • Platelet membrane glycoprotein IIIa

  • integrin beta chain, beta 3

  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

  • platelet glycoprotein IIIa
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein By similarity. SEQUENCE SIMILARITIES: Belongs to the integrin beta chain family. View All» Product Name: Anti-Zebrafish Integrin beta3 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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