Merck Millipore代理AB1934 Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular;抗整合素α1亚基抗体,胞质/细胞内store at -20℃

2025-06-27

货号:AB1934

品牌:Merck Millipore

规格:100UL

目录价:¥4192.00

市场价格:¥3563.20

会员价格:¥3353.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular | AB1934 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Integrin alpha1. Specificity determined by immunoprecipitation from a detergent extract of 35S methionine labeled neuroblastoma cells. The epitope recognized is on the cytoplasmic domain of the protein and it is thus intracellular. No cross-reactivity to alpha2, alpha3, alpha4, alpha5, alpha6, or alphaV integrin subunits. View All» Epitope: cytoplasmic/intracellular View All» Immunogen: Synthetic peptide derived from the COOH terminal sequence (cytoplasmic domain) of the rat alpha1 integrin subunit (KIGFFKRPLKKKMEK) coupled to KLH. View All» Species Reactivity:

  • Chicken

  • Horse

  • Goat

  • Human

  • Hamster

  • Monkey

  • Pig

  • Rat

  • Sheep

    View All» Application Notes: ELISA/RIA: 1:1,000. Western blot: 1:100-1:1000. ~200 kDa in non-reduced westerns Immunoprecipitation: 5 μL of antibody is sufficient to precipitate alpha1 containing integrin dimers from 5x10E6 cells (Rossinoi, 1990). Immunohistochemistry Suggested for use an acetone fixed tissue only. This antibody has been reported to react in 4% PFA fixed monkey tissue treated with citrate at 1:200 (Qin, 2003). Optimal working dilutions must be determined by end user. View All» Presentation: Neat rabbit antisera. Liquid containing 0.05% sodium azide as a preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to one year from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P56199 View All» Entrez Gene Number: NM_181501.1 View All» Gene Symbol:
    • ITGA1

    • CD49a

    • VLA1

    • VLA-1

      View All» Alternate Names: CD49a View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Immunoprecipitation

      • Radioimmunoassay

      • Western Blotting

      • Immunocytochemistry

      • Immunohistochemistry

        View All» Entrez Gene Summary: This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. View All» UniProt Summary: FUNCTION: SwissProt: P56199 # Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen.SIZE: 1179 amino acids; 130848 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.DOMAIN: SwissProt: P56199 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Integrin α1 Subunit Antibody, cytoplasmic/intracellular | AB1934 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»

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