货号：AB2200

品牌：Merck Millipore

规格：100Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-PRG4 Antibody | AB2200 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB2220 recognizes PRG4. View All» Molecular Weight: ~37 kDa View All» Epitope: C-Teminus View All» Immunogen: KLH-conjugated followed by PRG4 corresponding to the C-terminal region View All» Background Information: PRG4, Proteoglycan 4, is a human gene and is found in synovial tissue, cartilage, and liver. Small amounts are found in the lung. Isoform 1 is found in the kidney, lung, liver, heart and brain. The other Isoforms, C & D, are widely expressed. PRG4 is a lubricating glycoprotein containing chondroitin sulfate and keratan sulfate glycosaminoglycans. It is responsible for boundary lubrication at the cartilage surface. A disease associated with PRG4 is Jacobs’s syndrome which is an autosomal recessive disorder. View All» Species Reactivity:

• Mouse

• Human

• Horse

• Primate

• Rat
  View All» Species Reactivity Note: Proven to react in mouse. Predicted to react in rat, human, primate, and horse based on sequence homology. View All» Application Notes: Immunocytochemistry: Confocal IF analysis of N1E-115 using anti-PRG4 (1:500) Rabbit pAB (Red). Actin filaments have been labeled with Alexa Fluor 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue). View All» Control: Mouse Brain lysates View All» Quality Assurance: Western Blotting View All» Purification Method: Antigen affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3. View All» Storage Conditions: Stable for 1 year at 2-8ºC from date of receipt. View All» UniProt Number: Q96GM1 View All» Entrez Gene Number: NM_001127708.1 View All» Gene Symbol:
  • CACP

  • FLJ32635

  • HAPO

  • JCAP

  • Lubricin

  • MSF

  • OTTHUMP00000033580

  • SZP

  • bG174L6.2

  • lubricin
    View All» Alternate Names:
    • Megakaryocyte-stimulating factor

    • Superficial zone proteoglycan

    • articular superficial zone protein

    • bG174L6.2 (MSF: megakaryocyte stimulating factor )

    • megakaryocyte stimulating factor

    • proteoglycan 4

    • proteoglycan 4, (megakaryocyte stimulating factor,articular superficial zone protein, camptodactyly,arthropathy, coxa vara, pericarditis syndrome)
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] View All» UniProt Summary: CATALYTIC ACTIVITY: A 3-sn-phosphatidate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate.SUBCELLULAR lOCATION: Membrane; Multi-pass membrane proteinPotential. SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase family. View All» Product Name: Anti-PRG4 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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