货号：AB2212

品牌：Merck Millipore

规格：50UL

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho GluR4 (S862) Antibody | AB2212 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Cat. # AB2212 recognzies phospho GluR4 (S862). View All» Molecular Weight: ~105 kDa View All» Immunogen: Synthetic peptide from rat. View All» Modifications: Phosphorylation View All» Background Information: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. Direct phosphorylation of GluR4-containing receptors may regulate rapid excitatory synaptic transmission. In addition, phosphorylation of GluR4 S862. is both necessary and sufficient to deliver the receptor to the synapse and induce plasticity in early postnatal development. View All» Species Reactivity: Rat View All» Species Reactivity Note: Rat. May react with mouse, human, primate and dog based on sequence homology. Reactivity with other species has not been tested. View All» Application Notes: Western Blot Analysis:Cat. # AB2212 recognizes pGluR4 (S862) at 1:5,000 in rat brain cerebellum Lysate. View All» Control: Rat Brain Cerebellum lysate View All» Quality Assurance: Routinely tested on rat brain cerebellum lysate. View All» Presentation: Serum with 0.05% NaN3 View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: P19493 View All» Gene Symbol:

• GRIA4

• GLURD

• GluR-4

• GluR-D
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Brand Family: Chemicon View All» Product Name: Anti-phospho GluR4 (S862) Antibody | AB2212 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50µL View All» Format: Serum View All» Host: Rabbit View All»
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