货号：AB2234

品牌：Merck Millipore

规格：

目录价：￥4502.00

市场价格：￥3826.70

会员价格：￥3601.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Norepinephrine Transporter Antibody | AB2234 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB2234 recognizes norepinephrine transporter View All» Molecular Weight: ~69 kDa View All» Immunogen: Synthetic Linear Peptide View All» Background Information: The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. In the CNS, norepinephrine is involved in a number of physiological responses including mood, sleep regulation, alertness and arousal, both cognitive and non-cognitive expression of behaviors, and control of the endocrine and autonomic nervous systems. Peripherally, norepinephrine is present in sympathetic nerve endings and has full control of the sympathetic nervous system. Certain antidepressant medications act to raise norepinephrine, such as the SNRIs and the tricyclic antidepressants (TCAs). In essence, these medications prevent the norepinephrine transporter from serving its purpose. Norepinephrine therefore remains in the synapse longer, allowing it to reach more normal levels. Since the norepinephrine transporter is also thought to transport dopamine to some extent, SNRIs would also raise dopamine levels in the synapse. View All» Species Reactivity: Rat View All» Species Reactivity Note: Rat. May react with human, mouse, dog and cow based on sequence homology. Reactivity with other species has not been determined. View All» Control: PC12 lysate. View All» Quality Assurance: Routinely evaluated by western blot. View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified in 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3 View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: Q63380 View All» Entrez Gene Number: NP_001034 View All» Gene Symbol:

• NAT1

• NET

• NET1

• SLC6A5
  View All» Alternate Names:
  • Norepinephrine transporter

  • noradrenaline transporter

  • solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

  • solute carrier family 6 (neurotransmitter transporter, norepinephrine), member 5

  • solute carrier family 6 member 2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis (Kim et al., 2006 [PubMed 17146058]).[supplied by OMIM] View All» UniProt Summary: LOCATION: Membrane; Multi-pass membrane protein. SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) family View All» Product Name: Anti-Norepinephrine Transporter Antibody | AB2234 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Plasma Membrane View All» Format: Purified View All» Host: Rabbit View All»
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