货号：AB2251

品牌：Merck Millipore

规格：

目录价：￥5399.00

市场价格：￥4589.15

会员价格：￥4319.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-VGLUT2 Antibody | AB2251 View All» Replaces: Cat. # AB5907 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB2251 recognizes VGLUT2 View All» Molecular Weight: ~52 kDa View All» Immunogen: Peptide corresponding to the C-terminal of rat VGLUT-2. View All» Background Information: VGLUT2 is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity. View All» Species Reactivity:

• Mouse

• Rat
  View All» Species Reactivity Note: Tested on mouse and rat. Sequence homology 100% with rat. View All» Application Notes: Immunohistochemistry: Tested on mouse floating brain sections at 1:12,000. View All» Control: Rat Brain Lysate View All» Quality Assurance: Routinely evaluated by western blot on rat brain lysate. View All» Purification Method: GST Depletion View All» Presentation: GST-Depleted Sera; with 0.05% NaN3 View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt.Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. View All» UniProt Number: Q9JI12 View All» Entrez Gene Number: NM_020346.1 View All» Gene Symbol:
  • DNPI

  • VGLUT2

  • VGluT2
    View All» Alternate Names:
    • Differentiation-associated BNPI

    • Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter

    • Solute carrier family 17 member 6

    • differentiation-associated Na-dependent inorganic phosphate cotransporter

    • solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6

    • vesicular glutamate transporter 2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» UniProt Summary: FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.LOCATION: Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membraneBy similarity. Membrane; Multi-pass membrane proteinPotential. Cell junction › synapse › synaptosomeBy similarity. SPECIFICITY:Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, puteman, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus.Developmental stage Expressed in fetal brain.SIMILARITY:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily View All» Product Name: Anti-VGLUT2 Antibody | AB2251 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Target / Localization: Presynaptic View All» Format: Serum View All» Host: Guinea Pig View All»
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