货号：AB2252

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Adenosine A2b Receptor Antibody | AB2252 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB2252 recognizes Adenosine in human tissue. Not Recommended for Western blot. View All» Molecular Weight: Approx. 50 kDa View All» Epitope: Extracellular domain View All» Immunogen: KLH conjugated synthetic linear peptide of Adenosine corresponding to extracellular domain View All» Background Information: Adenosine controls many physiological processes such as energy transfer (ATP and ADP) and is found through out the body. There are 4 Adenosine receptors: A1, A2A, A2B, and A3. A2B, found on human mast cells, promote vasodilation and is also found throughout the body. Adenosine has been widely associated with hypoxia of many origins, including those associated with inflammation and tumorogenesis. A number of recent studies have implicated metabolic control of adenosine generation at sites of tissue hypoxia. Diseases associated with this protein are carcinomas, lymphomas, and melanomas. View All» Species Reactivity: Human View All» Species Reactivity Note: Human. May react with Horse, Chimpanzee, Rhesus Monkey and Dog based on sequence homology. Reactivity with other species has not been determined. View All» Applications Not Recommended: Western Blotting View All» Control: Human breast cancer tissue View All» Quality Assurance: Routinely evaluated by Immunohistochemistry on human breast cancer tissue. Not recommended for western blot.Immunohistochemistry: 1:500 - 1:1500 dilution of this antibody IHC-Select reagents used with HRP-DAB View All» Purification Method: Antigen affinity purified View All» Presentation: Purified antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 15mM NaCl with 0.05 NaN3. View All» Storage Conditions: Stable for 1 year at 2-8ºC from date of receipt. View All» UniProt Number: P29275 View All» Entrez Gene Number: NP_000667 View All» Gene Symbol:

• ADORA2

• ADORA2B
  View All» Alternate Names: adenosine A2b receptor View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family. View All» Product Name: Anti-Adenosine A2b Receptor View All» Concentration: 1mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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