货号：AB2265

品牌：Merck Millipore

规格：100Ug

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-VPAC1 Antibody | AB2265 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes VPAC1 at the cytoplasmic domain. View All» Molecular Weight: ~52 kDa observed. Multiple molecular weights of VPAC1 may be due to glycosylation. (Fabre, C, et al. (1993). Peptides. 14:483-489.) View All» Epitope: Cytoplasmic domain View All» Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic domain of VPAC1. View All» Background Information: The vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1 (VPAC1) is a member of a class II subfamily of G-protein-coupled receptors and has a high affinity for vasoactive intestinal peptide (VIP). VPAC1 has been associated with many different lung cancer cell lines. VPAC1 is thought to be activated by FXR and may contribute to the regulation of bile secretion to protect against gallstone disease. VPAC1 could be used to regulate VIPs and, in turn, inhibit breast cancer growth. VPAC1 has also been implicated in regulation of the anti-inflammatory effects of VIP. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected VPAC1 in ovarian carcinoma tissue. View All» Control: SK-OV-3 cell lysate View All» Quality Assurance: Evaluated by Western Blot in SK-OV-3 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected VPAC1 on 10 µg of SK-OV-3 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P97751 View All» Entrez Gene Number: NP_035833 View All» Gene Symbol:
  • VIPR1

  • PACAP-R-2

  • RCD1

  • VIP-R-1

  • VPAC1

  • VIRG

  • HVR1

  • VPCAP1R

  • VAPC1

  • VIPR

  • RDC1
    View All» Alternate Names:
    • Vasoactive intestinal polypeptide receptor 1

    • Pituitary adenylate cyclase-activating polypeptide type II receptor

    • vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry (Paraffin)

      • Western Blotting
        View All» UniProt Summary: FUNCTION: This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 2 family. View All» Product Name: Anti-VPAC1 View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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