货号：AB3070

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Urea Tranporter 2 Antibody | AB3070 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Rat Urea Transporter 2 (rUT2) View All» Immunogen: A 19 aa C-terminal peptide sequence from rat-UT2. This peptide is predicted to cytoplasmic. View All» Species Reactivity: Rat View All» Application Notes: Immunohistochemistry: 2-10 μg/mL in paraformaldehyde fixed sections of tissues. RUT2 has been localized in apical and sub-apical membranes of IMCD (Nielsen et al. 1996). Adherent cells can be fixed in 50% methanol-50% acetone or 1% paraformaldehyde.Western Blotting: 1-10 μg/mL using Chemiluminescence technique. An antibody made to rUT2 peptide detected a major band at ~97 kDa in rat renal inner medulla membranes (Nielsen et al. 1996). The open reading frames of the cDNA clones for rabbit and rat UT2 predicted a protein of only ~43 kDa (You et al. 1993; Smith et al. 1995; Nielsen et al. 1996). However, northern blots using these cDNAs revealed 2 distinct transcripts (2.9 and 4kb). The 97 kDa band correspond to the 4 kb transcript (Nielsen et al. 1996).ELISA: 1:100,000 using 50-100 ng of control peptide/well.Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS at 1 mg/mL, pH 7.4 with 0.1% BSA as stabilizer and 0.1% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q15849 View All» Entrez Gene Number: NM_007163.3 View All» Gene Symbol:

• SLC14A2

• HUT2

• hUT-A6

• FLJ16167

• UTR

• MGC119566

• UT-A2

• MGC119567

• UT2
  View All» Alternate Names: UT2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Immunohistochemistry

  • Western Blotting
    View All» Entrez Gene Summary: In mammalian cells, urea is the chief end-product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. Thus, the plasma membrane of erythrocytes and some renal epithelial cells exhibit an elevated urea permeability that is mediated by highly selective urea transporters. In mammals, 2 urea transporters have been identified: the renal tubular urea transporter, UT2, and the erythrocyte urea transporter, UT11 (SLC14A1; MIM 111000).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q15849 # Specialized low-affinity urea transporter. Mediates urea transport in kidney.SIZE: 397 amino acids; 43395 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Kidney.SIMILARITY: SwissProt: Q15849 ## Belongs to the urea transporter family. View All» Brand Family: Chemicon View All» Product Name: Anti-Urea Tranporter 2 Antibody | AB3070 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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