货号：AB3081

品牌：Merck Millipore

规格：50Ug

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Na+/H+ Exchanger-1 Antibody | AB3081 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Na+/H+ Exchanger 1 (NHE1). The immunogen peptide shows no significant homology with other NHE isoforms (NHE2-5). View All» Molecular Weight: 91 kDa View All» Immunogen: A 22 aa peptide within the cytoplasmic, C-terminal domain of rat NHE1, coupled to KLH. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Pig

• Rat
  View All» Application Notes: Western blot: 1-10 μg/mL using Chemiluminescence technique. ELISA: 1:100,000 using 50-100 ng control peptide per well. Optimal working dilutions must be determined by end user. View All» Control: Kidney tissue (basolateral membrane) View All» Purification Method: Immunoaffinity purified View All» Presentation: Affinity Purified immunoglobulin. Liquid in 100 mM Tris, pH 7.5 and 0.2% BSA and 0.05% sodium azide. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P19634 View All» Entrez Gene Number: NM_003047.2 View All» Gene Symbol:
  • SLC9A1

  • APNH

  • +H

  • APNH1

  • FLJ42224

  • NHE-1

  • Na

  • NHE1
    View All» Alternate Names: NHE1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting
      View All» UniProt Summary: FUNCTION: SwissProt: P19634 # Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.SIZE: 815 amino acids; 90763 Da SUBUNIT: Interacts with tescalcin, CHP and CHP2.SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Kidney and intestine.PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. & O-glycosylated.SIMILARITY: SwissProt: P19634 ## Belongs to the Na(+)/H(+) exchanger (TC 2.A.36.5.1) family. MISCELLANEOUS: Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation, the apparent affinity for internal H(+) is increased, resulting in a persistent rise in cytoplasmic pH." View All» Brand Family: Chemicon View All» Product Name: Anti-Na+/H+ Exchanger-1 Antibody | AB3081 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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