货号：AB3279

品牌：Merck Millipore

规格：100UL

目录价：￥5053.00

市场价格：￥4295.05

会员价格：￥4042.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Hexokinase Type II Antibody | AB3279 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with the Type II isozyme of rat hexokinase (102 kDa). No reactivity with the Type I or Type III isozymes of rat hexokinase by immunoblot or ELISA. Reactivity with human and hamster Type II isozyme has been confirmed by immunoblotting, and reactivity with Type II isozyme from other mammalian species is expected. View All» Molecular Weight: 102 kDa View All» Immunogen: Recombinant rat Type II hexokinase. View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western Blot: 1:5,000-1:10,000. Immunocytochemistry using indirect immunofluorescence. ELISA Optimal working dilutions must be determined by the end user. View All» Control: insulin-responsive tissues such as skeletal muscle View All» Purification Method: Immunodepleted Serum View All» Presentation: Liquid. Partially Purified rabbit Serum. Antibodies reactive with the Type I isozyme were present in the original antiSerum; these were removed by affinity chromatography on a column of immobilized Type I isozyme, and the affinity-depleted Serum restored to original volume. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P52789 View All» Entrez Gene Number: NM_000189.4 View All» Gene Symbol:
  • HK2

  • HKII

  • Hexokinase-2

  • HXK2

  • DKFZp686M1669

  • EC 2.7.1.1
    View All» Alternate Names: HK II View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunocytochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. View All» UniProt Summary: SIZE: 917 amino acids; 102380 Da SUBUNIT: Monomer (By similarity).SUBCELLULAR LOCATION: Mitochondrion outer membrane (By similarity). Note=Its hydrophobic N-terminal sequence may be involved in membrane binding (By similarity).TISSUE SPECIFICITY: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.DOMAIN: SwissProt: P52789 The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.SIMILARITY: Belongs to the hexokinase family.MISCELLANEOUS: In vertebrates there are four major glucose- phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). View All» Brand Family: Chemicon View All» Product Name: Anti-Hexokinase Type II Antibody | AB3279 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Purified View All» Host: Rabbit View All»
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