货号：AB3402P

品牌：Merck Millipore

规格：50Ug

目录价：￥6047.00

市场价格：￥5139.95

会员价格：￥4837.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Agouti Related Protein Antibody | AB3402P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes AGRP. The immunogen shows no significant sequence homology with Agouti, tubby, tub, TULP1 or TULP2. SPECIES REACTIVITIES: The immunogen sequence is 85% homologous with human and bovine. Reactivity with other species has not been confirmed. View All» Immunogen: A 15 amino acid peptide near the C-terminus of mouse AGRP (Shutter et al. 1997; Ollmann et al. 1997). View All» Background Information: Agouti-related peptide-expressing (AgRP) neurons seem to be critical for the acute regulation of eating. The AgRP ptrotein is a strong antagonis of MC3-R and MC4-R and is expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney. View All» Species Reactivity: Mouse View All» Application Notes: Western blot: 1-10 μg/mL using ECL. ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well. Optimal working dilutions must be determined by the end user. View All» Presentation: Liquid in phosphate buffered saline containing 0.1% BSA. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: O00253 View All» Entrez Gene Number:

• NM_001138.1

• NM_007316.1
  View All» Gene Symbol:
  • AGRP

  • Agrt

  • ASIP2

  • MGC118963

  • AGRT

  • ART
    View All» Alternate Names: AGRP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting
      View All» Entrez Gene Summary: Agouti-related protein is an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation. Agouti-related protein is alternatively spliced into 2 variants which differ in 5' untranslated sequence length. View All» UniProt Summary: FUNCTION: SwissProt: O00253 # Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.SIZE: 132 amino acids; 14440 Da SUBCELLULAR LOCATION: Secreted (By similarity).TISSUE SPECIFICITY: Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.DOMAIN: SwissProt: O00253 The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.DISEASE: SwissProt: O00253 # Defects in AGRP may be a cause of autosomal dominant obesity [MIM:601665].SIMILARITY: Contains 1 agouti domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Agouti Related Protein Antibody | AB3402P View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-153323.htm
      © Merck Millipore代理AB3402P Anti-Agouti Related Protein Antibody;store at -20℃，产品报价联系微信jinshanbio