Merck Millipore代理AB3854 UBCH1, RBX-200UL;已停产

2025-06-27

货号:AB3854

品牌:Merck Millipore

规格:EA

目录价:询价

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-UbcH1 Antibody | AB3854 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes UbcH1 (E2-25K). View All» Immunogen: Full length, highly purified, UbcH1 protein. View All» Background Information: Unique among ubiquitin conjugating enzymes, E2-25K (UbcH2) catalyses the synthesis of poly-Ub chains linked via K48-G76 isopeptide bonds in vitro. It has been observed to form cyclic polyubiquitin and to add NEDD8 to poly-Ub chains. E2-25K functions only with mammalian E1. View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:100-1:1000 Optimal working dilutions must be determined by end user. View All» Presentation: Protein A purified immunoglobulin in liquid PBS, pH 7.4, with 20% glycerol. View All» Storage Conditions: Maintain at -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. May be stored at 2-8°C for up to 1 month. View All» UniProt Number: P51965 View All» Entrez Gene Number:

  • NM_003341.3

  • NM_182666.1

    View All» Gene Symbol:
    • UBE2E1

    • UbcH6

    • UBCH6

    • EC 6.3.2.19

      View All» Alternate Names: E2-25K; E2 Ubiquitin-conjugating Enzyme View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P51965 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.SIZE: 193 amino acids; 21404 Da SUBUNIT: Interacts with RNF14.SIMILARITY: SwissProt: P51965 ## Belongs to the ubiquitin-conjugating enzyme family. View All» Brand Family: Chemicon View All» Product Name: Anti-UbcH1 Antibody | AB3854 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»

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