货号：AB4098

品牌：Merck Millipore

规格：

目录价：￥3767.00

市场价格：￥3201.95

会员价格：￥3013.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cathepsin S Antibody | AB4098 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes mature human Cathepsin S. This antibody detects a band of approximately 30 kDa corresponding to the single chain proteolyitc product in Western blot analysis of PC-3 cell lysate. Does show some non-specific cross reactivity at 50 kDa and higher. View All» Immunogen: Synthetic peptide corresponding to amino acid residues 229-246 of human Cathepsin S. View All» Background Information: Cathepsin S is a lysosomal cysteine protease expressed in numerous tissues. Pro-Cathepsin S (37kDa) is processed to the active form (28 kDa single chain). It is reportedly involved in antigen presentation, general protein catabolism, and tumor progression. Because of its redistribution or increased levels in human and animal tumors, cathepsin S may have a role in invasion and metastasis. View All» Species Reactivity: Human View All» Control: Western blot positive control: PC-3 cell line View All» Presentation: Liquid in 0.02M Phosphate Buffer, 0.25M NaCl, with 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C for up to 12 months from date of receipt. View All» UniProt Number: P25774 View All» Entrez Gene Number: NM_004079.3 View All» Gene Symbol:

• CTSS

• MGC3886

• EC 3.4.22.27
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Transcript variants utilizing alternative polyadenylation signals exist for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P25774 # Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.SIZE: 331 amino acids; 37496 Da SUBUNIT: Monomer.SUBCELLULAR LOCATION: Lysosome.SIMILARITY: SwissProt: P25774 ## Belongs to the peptidase C1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Cathepsin S Antibody | AB4098 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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