金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: IFN-alpha/beta R2 Long Name: Interferon alpha/beta Receptor 2 Aliases: IFNAR2 Entrez Gene IDs: 3455 (Human); 15977 (Mouse) Background: IFN-alpha/beta R2 IFN-alpha/beta R2, also known as IFNAR2, is a 100 kDa component of the class II cytokine receptor that binds the type I interferons IFN-alpha, IFN-beta, and IFN-omega. IFN-alpha/beta R2 associates with the 125 kDa IFN-alpha/beta R1 component to form a receptor complex that transmits antiviral and antiproliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation. A soluble form of the protein, corresponding to the extracellular ligand-binding domain, is generated by alternative splicing.