货号：AB5028

品牌：Merck Millipore

规格：

目录价：￥3908.00

市场价格：￥3321.80

会员价格：￥3126.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Endorphin Antibody, β | AB5028 View All» Replaces: CBL98 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Beta-endorphin. Cross reactivity: Met-enkephalin 0.03%, Leu-enkephalin 0.02% and beta-Lipotropin 0.34%. View All» Immunogen: Synthetic peptide (H-Thy-Gly-Gly-Phe-Met-Thr-Ser-Lys- Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala- Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH) from human beta-endorphin conjugated to thyroglobulin. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunohistochemistry: 1:500-1:1,000 using immunofluorescence and 1:5,000-1:10,000 for indirect avidin-biotin. Not recommended for traditional formalin fixed paraffin tissues. 4% formalin fixed, resin embedded tissues can be used. Antibodies should be diluted in simple solutions (PBS plus 1% BSA) only. Blocking should not contain serum. RIA: 1:10,000; sensitivity 120 pg/sample; IC50 - 1 ng/sample) Optimal working dilutions must be determined by the end user. View All» Applications Not Recommended: Immunohistochemistry (Paraffin) View All» Presentation: Purified immunoglobulin Liquid. Contains 0.1% sodium azide as a preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P01189 View All» Entrez Gene Number:
  • NM_000939.2

  • NM_001035256.1
    View All» Gene Symbol:
    • POMC

    • pro-ACTH-endorphin

    • adrenocorticotropin

    • beta-LPH

    • POC

    • gamma-LPH

    • LPH

    • ACTH

    • corticotropin

    • beta-endorphin

    • beta-MSH

    • alpha-MSH

    • pro-opiomelanocortin

    • proopiomelanocortin

    • Pro-opiomelanocortin

    • corticotropin-lipotrophin

    • NPP

    • MSH

    • met-enkephalin

    • CLIP

    • gamma-MSH
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Radioimmunoassay
        View All» Entrez Gene Summary: This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. View All» UniProt Summary: FUNCTION: SwissProt: P01189 # Beta-endorphin and Met-enkephalin are endogenous opiates.SIZE: 267 amino acids; 29424 Da TISSUE SPECIFICITY: ACTH and MSH are produced by the pituitary gland.PTM: Specific enzymatic cleavages at paired basic residues yield the different active peptides. & O-glycosylated; reducing sugar is probably N- acetylgalactosamine.DISEASE: SwissProt: P01189 # Defects in POMC may be associated with susceptibility to obesity [MIM:601665]. & Defects in POMC are the cause of pro-opiomelanocortinin deficiency [MIM:609734]. Affected individuals present early-onset obesity, adrenal insufficiency and red hair.SIMILARITY: SwissProt: P01189 ## Belongs to the POMC family. View All» Brand Family: Chemicon View All» Product Name: Anti-Endorphin Antibody, β | AB5028 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µg View All» Format: Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-153762.htm
        © Merck Millipore代理AB5028 ENDORPHIN (BETA), RB X-50UG，产品报价联系微信jinshanbio