Merck Millipore代理AB5087 Anti-Melanocyte Stimulating Hormone α Antibody;抗黑素细胞刺激素α抗体store at -20℃

2025-06-28

货号:AB5087

品牌:Merck Millipore

规格:50UL

目录价:¥5974.00

市场价格:¥5077.90

会员价格:¥4779.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Melanocyte Stimulating Hormone Antibody, α | AB5087 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal. View All» Immunogen: MSH conjugated with bovine thyroglobulin. View All» Species Reactivity: Mammals View All» Application Notes: Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue. RIA: 1:250,000-1:300,000. Optimal working dilutions must be determined by the end user. View All» Control: Hypothalamus View All» Purification Method: Unpurified View All» Presentation: Sheep Serum. Liquid. Contains no preservative. View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P01189 View All» Entrez Gene Number:

  • NM_000939.2

  • NM_001035256.1

    View All» Gene Symbol:
    • POMC

    • LPH

    • NPP

    • POC

    • ACTH

    • CLIP

      View All» Alternate Names:
      • alpha-MSH

      • POMC

      • Pro-opiomelanocortin

      • Corticotropin-lipotropin precursor

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Immunohistochemistry

        • Radioimmunoassay

          View All» Entrez Gene Summary: This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. View All» UniProt Summary: FUNCTION: MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.SIZE: 267 amino acids; 29424 Da TISSUE SPECIFICITY: Melanocytes and corticoadrenal tissue. Produced by the pituitary gland.SIMILARITY: Belongs to the POMC family. View All» Brand Family: Chemicon View All» Product Name: Anti-Melanocyte Stimulating Hormone Antibody, α | AB5087 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 μL View All» Format: Serum View All» Host: Sheep View All»

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