货号：AB5250-200UL

品牌：Merck Millipore

规格：200UL

目录价：￥9712.00

市场价格：￥8255.20

会员价格：￥7769.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Potassium Channel TASK1 Antibody | AB5250-200UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The epitope is specific for TASK1 and is not present in any other known proteins tested so far. SPECIES REACTIVITIES: The epitope is also highly conserved between mouse and rat (17/18 residues identical) but other species have not been tested. View All» Immunogen: A purified peptide (TASK) corresponding to amino acid residues 252-269 in the cytoplasmic C-terminus of human TASK1 (Accession O14649). View All» Species Reactivity:

• Human

• Rat
  View All» Application Notes: Western blot: 1:200 using ECL on rat brain membranes. Immunohistochemistry on rat brain sections. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: O14649 View All» Entrez Gene Number: NM_002246 View All» Gene Symbol:
  • KCNK3

  • KT3.1

  • K2p3.1

  • TASK-1

  • TASK1

  • OAT1

  • TBAK1
    View All» Alternate Names: TWIK-Related Acid Sensitive; TASK-1; cTBAK; Kcnk3 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq] View All» UniProt Summary: FUNCTION: pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. SIZE: 43518 Da [This is the MW of the unprocessed precursor].SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). TISSUE SPECIFICITY: Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon. MISCELLANEOUS: Inhibited by external acidification. Activated by halothane and isoflurane. SIMILARITY: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. View All» Brand Family: Chemicon View All» Product Name: Anti-Potassium Channel TASK1 Antibody | AB5250-200UL View All» Concentration: 120 mg/200 mL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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