货号：AB5314

品牌：Merck Millipore

规格：100UL

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Carboxypeptidase H Antibody, C-terminus | AB5314 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: C-terminus of Carboxypepdidase H. View All» Epitope: C-terminus View All» Immunogen: Synthetic peptide corresponding to the C-terminus of Carboxypepdidase H conjugated to KLH. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunocytochemistry on AtT-20 cell line: 1:100-1:500. Western blot: 1:500-1:2,000. Carboxypeptidase H precursor migrates at 53 kDa while active enzyme migrates at about 48 kDa. Immunoprecipitation: 1:250-1:1,000 Optimal working dilutions must be determined by end user. View All» Presentation: Serum with 0.02% sodium azide. View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P16870 View All» Entrez Gene Number: NM_001873.1 View All» Gene Symbol:
  • CPE

  • CPH

  • EC 3.4.17.10
    View All» Alternate Names: CPH; Carboxypeptidase E View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunoprecipitation

    • Western Blotting

    • Immunocytochemistry
      View All» Entrez Gene Summary: This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. View All» UniProt Summary: FUNCTION: SwissProt: P16870 # Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.COFACTOR: Binds 1 zinc ion per subunit (By similarity).SIZE: 476 amino acids; 53151 Da SUBCELLULAR LOCATION: Secreted. Note=Secretory granules of pancreatic islets, adrenal gland, pituitary and brain.SIMILARITY: SwissProt: P16870 ## Belongs to the peptidase M14 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Carboxypeptidase H Antibody, C-terminus | AB5314 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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