货号：AB5376-50UL

品牌：Merck Millipore

规格：50UL

目录价：￥5027.00

市场价格：￥4272.95

会员价格：￥4021.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Potassium Channel Kir2.3 Antibody | AB5376-50UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Kir2.3 protein. The epitope is specific for Kir2.3 and is not present in any other known protein. SPECIES REACTIVITIES: The immunogen sequence is identical in mouse. It is highly homologous in hamster, human and Xenopus (18/20 residues). Other species have not been tested. View All» Immunogen: Purified peptide from rat Kir2.3 (amino acids 418-437) (Accession P52190). View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:200 using ECL on rat brain membranes. Immunohistochemistry on rat brain sections. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 2 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P48050 View All» Entrez Gene Number:

• NM_004981.1

• NM_152868.1
  View All» Gene Symbol:
  • KCNJ4

  • IRK3

  • MGC142068

  • MGC142066

  • HRK1

  • Kir2.3

  • hIRK2

  • HIRK2

  • HIR

  • OTTHUMP00000028922
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Western Blotting
      View All» Entrez Gene Summary: Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P48050 # This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).SIZE: 445 amino acids; 49500 Da SUBUNIT: Homomultimeric and heteromultimeric association with Kir2.1, resulting in an enhanced G-protein-induced current. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking (By similarity).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Heart, skeletal muscle, and several different brain regions among which the hippocampus.DOMAIN: SwissProt: P48050 The Val/Gly/Ala/Pro stretch may have a functional role in the conductance or permeation properties.SIMILARITY: Belongs to the inward rectifier-type potassium channel family. View All» Brand Family: Chemicon View All» Product Name: Anti-Potassium Channel Kir2.3 Antibody | AB5376-50UL View All» Concentration: 15 μg/50 μL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-153986.htm
      © Merck Millipore代理AB5376-50UL Anti-Potassium Channel Kir2.3 Antibody;store at -20℃，产品报价联系微信jinshanbio