货号：AB5378-200UL

品牌：Merck Millipore

规格：200UL

目录价：￥9712.00

市场价格：￥8255.20

会员价格：￥7769.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-HCN2 Antibody | AB5378-200UL View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes HCN2 protein. The epitope is specific for HCN2 and is not present in any other known protein. View All» Immunogen: Purified peptide from human HCN2 (amino acids 147-161) (Accession CAB42602). View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:200-1:1,000 using ECL on rat brain membranes. Immunohistochemistry on rat brain membrane sections. Dilutions should be made using a carrier protein such as BSA (1-3%) Optimal working dilutions must be determined by the end user. View All» Control: CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen. The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min). View All» Storage Conditions: Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9UL51 View All» Entrez Gene Number: NM_001194.3 View All» Gene Symbol:

• HCN2

• BCNG-2

• HAC-1

• BCNG2
  View All» Alternate Names: Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 2; BCNG2; HAC-1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Western Blotting
    View All» UniProt Summary: FUNCTION: SwissProt: Q9UL51 # Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity).SIZE: 889 amino acids; 96950 Da SUBUNIT: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. Heteromultimer with HCN1. Interacts with KCNE2 (By similarity).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Highly expressed throughout the brain. Detected at low levels in heart.DOMAIN:SwissProt: Q9UL51 The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.SIMILARITY: Belongs to the potassium channel HCN family. & Contains 1 cyclic nucleotide-binding domain. MISCELLANEOUS: Inhibited by extracellular cesium ions. View All» Brand Family: Chemicon View All» Product Name: Anti-HCN2 Antibody | AB5378-200UL View All» Concentration: 60 μg/200 μL(after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µL View All» Format: Affinity Purified View All» Host: Rabbit View All»
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