货号：AB5398

品牌：Merck Millipore

规格：50UL

目录价：￥6742.00

市场价格：￥5730.70

会员价格：￥5393.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, C-terminus | AB5398 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Vanilloid receptor like protein 1 (VRL-1). Immunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates that this antibody is of high specificity. View All» Epitope: C-terminus View All» Immunogen: Peptide corresponding to the C-terminal 18 amino acids of the rat VRL-1 protein sequence (Acc#: AAD26364). This immunogen sequence is 100% conserved in the mouse growth factor regulated calcium channel (Acc#: AB021665) View All» Species Reactivity: Rat View All» Non-Reactive Species: Human View All» Application Notes: Immunohistochemistry: 1:1,000-1:2,000 on rat dorsal root ganglia. Optimal working dilutions must be determined by end user. View All» Presentation: Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue. View All» Storage Conditions: Maintain lyophilized material at -20°C to -70°C for up to 6 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9Y5S1 View All» Entrez Gene Number: NM_016113.3 View All» Gene Symbol:

• TRPV2

• VRL

• TrpV2

• VRL-1

• OTRPC2

• MGC12549

• VRL1
  View All» Alternate Names: VRL-1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunohistochemistry View All» Entrez Gene Summary: This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y5S1 # Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.SIZE: 764 amino acids; 85981 Da SUBUNIT: Homotetramer (Probable). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with RGA (By similarity).SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.PTM: N-glycosylated (By similarity). & Phosphorylated by PKA (By similarity).SIMILARITY: SwissProt: Q9Y5S1 ## Belongs to the transient receptor family. TrpV subfamily. & Contains 3 ANK repeats. View All» Brand Family: Chemicon View All» Product Name: Anti-Vanilloid Receptor Like Protein 1 Antibody, pain, C-terminus | AB5398 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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