货号：AB5398P

品牌：Merck Millipore

规格：20Ug

目录价：￥6742.00

市场价格：￥5730.70

会员价格：￥5393.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vanilloid Receptor Like Protein Antibody, pain, C-terminus | AB5398P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Vanilloid receptor like protein 1 (VRL-1). Immunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates specific staining in a subpopulation of sensory neurons. View All» Epitope: C-terminus View All» Immunogen: Peptide corresponding to the C-terminal 18 amino acids of the rat VRL-1 protein sequence (Acc#: AAD26364). This immunogen sequence is 100% conserved in the mouse growth factor regulated calcium channel (Acc#: AB021665) View All» Species Reactivity: Rat View All» Non-Reactive Species: Human View All» Application Notes: Western blot: 0.5-1 μg/mL Immunohistochemistry: 0.5-1.0 μg/mL on rat dorsal root ganglia and spinal cord. Immunocytochemistry: 0.5-1.0 μg/mL on rat dorsal root ganglia and spinal cord. Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Lyophilized. Contains no preservative. Reconstitute with 20 μL of sterile distilled water. Centrifuge if necessary to remove any residue. View All» Storage Conditions: Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Glycerol (1:1) can be assed to additional stability. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q9Y5S1 View All» Entrez Gene Number: NM_016113.3 View All» Gene Symbol:

• TRPV2

• VRL

• TrpV2

• VRL-1

• OTRPC2

• MGC12549

• VRL1
  View All» Alternate Names: VRL-1 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Western Blotting

  • Immunocytochemistry

  • Immunohistochemistry
    View All» Entrez Gene Summary: This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. View All» UniProt Summary: FUNCTION: SwissProt: Q9Y5S1 # Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.SIZE: 764 amino acids; 85981 Da SUBUNIT: Homotetramer (Probable). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with RGA (By similarity).SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.PTM: N-glycosylated (By similarity). & Phosphorylated by PKA (By similarity).SIMILARITY: SwissProt: Q9Y5S1 ## Belongs to the transient receptor family. TrpV subfamily. & Contains 3 ANK repeats. View All» Brand Family: Chemicon View All» Product Name: Anti-Vanilloid Receptor Like Protein Antibody, pain, C-terminus | AB5398P View All» Concentration: 1 mg/mL (after reconstitution) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 20 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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