货号：AB5421

品牌：Merck Millipore

规格：

目录价：￥4481.00

市场价格：￥3808.85

会员价格：￥3584.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody | AB5421 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Vesicular Glutamate Transporter 3 (VGLUT3). The antiserum has been tested on tissue sections from the rat central nervous system (CNS) using immunofluorescence histochemistry. The staining pattern present in cell bodies obtained with the guinea pig VGLUT3 antiserum is in agreement with the described expression pattern of VGLUT3 mRNA The staining pattern obtained in both cell bodies and nerve fibers with the guinea pig VGLUT3 antiserum coincides with the described distribution of VGLUT3 immunoreactivity obtained with other VGLUT3 antisera (Fremeau, 2002; Gras, 2002; Schäfer, 2002). Preabsorption of the VGLUT3 antiserum with the immunogen peptide (Catalog number AG320) eliminates all immunostaining. View All» Molecular Weight: ~65 kDa View All» Immunogen: Synthetic peptide from rat VGLUT3 protein. View All» Background Information: Vesicular Glutamate Transporter 3 (VGLUT3) is a multipass membrane protein restricted to synaptic vesicles of glutamergic neurons. It is specifically expressed in amygdala, cerbellum, hippocampus, medulla, spinal cord, and thalamus. View All» Species Reactivity: Rat View All» Species Reactivity Note: Rat. It is expected that the antibody may also react with mouse based on sequence homology (85%). Other species have not yet been tested. View All» Application Notes: Immunohistochemistry: 1:5,000-1:10,000 dilution of a previous lot was used with immunofluorescence using cyanine-conjugated secondary antibodies.Optimal working dilutions must be determined by end user. View All» Control: Brain, VGLUT3 Control peptide available (Catalogue No. AG320) View All» Quality Assurance: Evaluated by Western Blot on PC12 lysates.Western Blot Analysis: 1:500 dilution of this antibody detected VGLUT3 on 10 μg of PC12 lysates. View All» Purification Method: Unpurified View All» Presentation: Guinea pig serum. Liquid. Contains no preservative. View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: Q8NDX2 View All» Entrez Gene Number: NM_139319.1 View All» Gene Symbol:

• VGLUT3

• VGluT3

• SLC17A8

• DFNA25
  View All» Alternate Names:
  • Solute carrier family 17 member 8

  • deafness, autosomal dominant 25

  • solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

  • vesicular glutamate transporter 3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunocytochemistry

    • Immunohistochemistry

    • Western Blotting
      View All» UniProt Summary: FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (By similarity). Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome (By similarity). TISSUE SPECIFICITY: Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus. SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. SIZE: 589 amino acids; 64991 Da View All» Brand Family: Chemicon View All» Product Name: Anti-Vesicular Glutamate Transporter 3 (VGLUT3) Antibody | AB5421 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Target / Localization: Presynaptic View All» Format: Serum View All» Host: Guinea Pig View All»
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