金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: NKG2D/CD314 Long Name: Natural Killer G2D Aliases: CD314; KLRK1 Entrez Gene IDs: 22914 (Human); 27007 (Mouse) Background: NKG2D NKG2D is a type II transmembrane protein with an extracellular C-type lectin domain. It occurs as a disulfide-linked homodimer that associates with either the DAP12 or DAP10 transmembrane adapter proteins. NKG2D is expressed on NK cells and some T cell subsets, where it functions as an activating receptor to trigger cytolytic activity and cytokine secretion. Ligands for human NKG2D include MICA, MICB, and ULBP-1, -2, -3, and -4. Mouse NKG2D ligands include H60, MULT-1, and Rae-1 alpha, beta, gamma, delta, and epsilon.