R&D Systems代理FAB2585C Human NG2/MCSP PerCP MAb (Clone LHM-2) (100 TESTS)

2025-06-28

货号:FAB2585C

品牌:R&D Systems

规格:100TESTS

目录价:¥5130.00

市场价格:¥4104.00

会员价格:¥4104.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Molecule Information: NG2/MCSP Long Name: Chondroitin Sulfate Proteoglycan NG2/Melanoma Associated Chondroitin Sulfate Proteoglycan Aliases: AN2; CSPG4; HMW-MAA; MCSP; MCSPG; MEL-CSPG Entrez Gene IDs: 1464 (Human); 121021 (Mouse); 81651 (Rat) Background: NG2/MCSP

    View NG2 IHC images. NG2 (neuron/glia-type 2 antigen; also MCSP/melanoma chondroitin sulfate proteoglycan) is a 250 - 500 kDa type I integral membrane proteoglycan found on synantocytes (NG2+ glia), vascular pericytes, chondroblasts, macrophages and melanoma cells. It binds multiple components of the ECM, and serves as a ligand for alpha3beta1 and alpha4beta1 integrins. Mature human NG2 is 2293 amino acids (aa) in length. It contains a large 2195 aa extracellular region (aa 30 - 2224) and a short, 79 aa cytoplasmic tail. NG2 is variably glycanated. Without proteoglycan, NG2 is expressed as a 250 kDa glycoprotein. Juxtamembrane proteolysis generates a soluble ECD that noncovalently associates with the transmembrane fragment. Over aa 1583 - 2224, human NG2 is 81% aa identical to both mouse and canine NG2.

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