R&D Systems代理FAB330A Human CXCR1/IL-8 RA Allophycocyanin MAb (Clone 42705) (100 TESTS)

2025-06-27

货号:FAB330A

品牌:R&D Systems

规格:100 TESTS

目录价:¥4540.00

市场价格:¥3632.00

会员价格:¥3632.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Molecule Information: CXCR1/IL-8 RA Long Name: Interleukin 8 Receptor A Aliases: CD181; IL8RA Entrez Gene IDs: 3577 (Human); 227288 (Mouse); 54258 (Rat) Background: CXCR1 CXCR1, also known as IL-8 RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8 RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness.

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