R&D Systems代理FAB6814A Mouse CD79B Allophycocyanin Affinity Purified PAb (100 TESTS)-试剂-金山科研平台

R&D Systems代理FAB6814A Mouse CD79B Allophycocyanin Affinity Purified PAb (100 TESTS)

2025-06-28

货号：FAB6814A

品牌：R&D Systems

规格：100TESTS

目录价：￥4700.00

市场价格：￥3760.00

会员价格：￥3760.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: CD79B Aliases: B29; CD79B; IGB Entrez Gene IDs: 974 (Human); 15985 (Mouse); 171055 (Rat) Background: CD79B

View CD79B IHC images. CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 37-39 kDa member of the Ig-Superfamily. It is expressed on B cells, and forms a covalent heterodimer with CD79A. This complex interacts noncovalently with membrane Ig, forming the B cell antigen receptor. Within this complex, membrane Ig detects antigen while CD79A/B initiates signaling. CD79B is also required for formation of pre-B cells during B cell development. Mature mouse CD79B is a 203 amino acid (aa) type I transmembrane glycoprotein (aa 26-228). It contains an extracellular region with one V-type Ig-like domain (aa 41-132) and an ITAM-containing cytoplasmic domain (aa 181-228). CD79B may migrate as two bands in SDS-PAGE. One defines the standard 37 kDa form, while a second represents one of two possible isoforms, the first of which is an underglycosylated full-length CD79B, and the second of which is an alternative splice form that likely lacks the C-terminal 32 amino acids. Mouse CD79A and CD79B share only 24% aa identity. Over aa 29-158, mouse CD79B shares 54% and 78% aa identity with human and rat CD79B, respectively.

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