金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: TRAIL/TNFSF10 Long Name: TNF-related Apoptosis-inducing Ligand Aliases: CD253; TNFSF10 Entrez Gene IDs: 8743 (Human); 22035 (Mouse) Background: TRAIL/TNFSF10 TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.