R&D Systems代理FAB7005G Mouse VISTA/B7-H5/PD-1H Alexa Fluor 488 Aff Pur PAb (100 TESTS)-试剂-金山科研平台

R&D Systems代理FAB7005G Mouse VISTA/B7-H5/PD-1H Alexa Fluor 488 Aff Pur PAb (100 TESTS)

2025-06-28

货号：FAB7005G

品牌：R&D Systems

规格：100TESTS

目录价：￥4700.00

市场价格：￥3760.00

会员价格：￥3760.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Gi24/VISTA/B7-H5 Aliases: 4632428N05Rik; B7-H5; C10orf54; Dies1; Gi24; SISP1; VISTA Entrez Gene IDs: 64115 (Human); 74048 (Mouse); 690899 (Rat) Background: Gi24

View Gi24 IHC images. Platelet receptor Gi24 (also known as Dies1 [Differentiation of ESC-1], SISP1 and C10orf54) is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

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