金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: ChemR23 Long Name: Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23 Aliases: Dez; Gpcr27; cmklr1 Entrez Gene IDs: 1240 (Human); 14747 (Mouse) Background: ChemR23 ChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.