金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: SIGIRR Long Name: Single lg IL-1 Related Protein Aliases: TIR8 Entrez Gene IDs: 59307 (Human); 24058 (Mouse) Background: SIGIRR Single Ig domain containing IL-1 receptor-related molecule (SIGIRR) is a subtype of the IL-1 R family that differs from the other members by having only one Ig domain in its extracellular region. SIGIRR is widely expressed and is present in all cells and tissues examined. Mouse and human SIGIRR share 82% amino acid sequence identity. The ligand and signaling mechanism for SIGIRR have not been identified.