金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:4.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (50 µL), Serum (50 µL), EDTA Plasma (50 µL), Heparin Plasma (50 µL) Sensitivity:2.8 pg/mL Assay Range:7.81 - 500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma) Specificity:Natural and recombinant mouse IL-17A/F heterodimer Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: IL-17A/F Heterodimer Long Name: Interleukin 17 A/F Background: IL-17 Ligands The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.